Wet AMD — Deal Benchmarks & Valuation
Market Analysis
Wet AMD is one of the most actively transacted indications in ophthalmology licensing. Phase 2 deals for wet amd carry a median total deal value of $3.6B, with upfront payments ranging from $423M to $1.1B. The recommended deal structure allocates approximately 21% to upfront payments and 79% to milestones.
Milestone structures for wet amd deals allocate $569M to development milestones, $712M to regulatory milestones, and $1.6B to commercial milestones. Royalty rates range from 10.2% to 20.4% at the base tier, with tiered escalation reaching 14.2%-24.4% on peak sales.
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