Skip to main content

Diabetic Retinopathy — Deal Benchmarks & Valuation

Median Upfront
$682M
Range: $376M - $975M
Total Deal Value
$3.2B
Range: $2.1B - $4.3B
Royalty Rate
9.9% - 19.7%
Tiered up to 23.7%
Dev Milestones
$506M
Range: $342M - $672M

Market Analysis

Diabetic Retinopathy is one of the most actively transacted indications in ophthalmology licensing. Phase 2 deals for diabetic retinopathy carry a median total deal value of $3.2B, with upfront payments ranging from $376M to $975M. The recommended deal structure allocates approximately 21% to upfront payments and 79% to milestones.

Milestone structures for diabetic retinopathy deals allocate $506M to development milestones, $632M to regulatory milestones, and $1.4B to commercial milestones. Royalty rates range from 9.9% to 19.7% at the base tier, with tiered escalation reaching 13.9%-23.7% on peak sales.

Customize these benchmarks for your asset

Adjust phase, modality, competitive position, and 10+ other parameters.

Open Calculator

Frequently Asked Questions

What are typical deal terms for diabetic retinopathy licensing?
Phase 2 diabetic retinopathy licensing deals average $682M in upfront payments with $3.2B total deal value. The 21/79 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for diabetic retinopathy deals?
Base royalty rates for diabetic retinopathy transactions range from 9.9% to 19.7%, with tiered escalations reaching 13.9%-23.7% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are diabetic retinopathy deal milestones structured?
Diabetic Retinopathy deals allocate approximately 79% of total deal value to milestones. Development milestones ($506M) make up the largest share, followed by commercial milestones ($1.4B) and regulatory milestones ($632M).
PRO

Full Benchmark Analysis

Complete deal term ranges, comparable transactions, and negotiation insights.

Start 7-Day Free Trial

$299/mo after trial · Cancel anytime

Ready to Calculate Your Deal Terms?

Get instant, customized benchmarks based on real market data from 1,600+ biopharma licensing deals.

Start Calculating
For Funds & Advisors

Need the full deal landscape?

The Deal Intelligence Brief covers every modality and deal structure for this indication — 52 deal calculations, AI strategic narrative, comparable transactions, partner matching, and white-label branding. Delivered in 24 hours.

Configure Brief — $2,500All-inclusive · White-label · Walkthrough included