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RSV — Deal Benchmarks & Valuation

Median Upfront
$826M
Range: $481M - $1.1B
Total Deal Value
$3.2B
Range: $2.2B - $4.2B
Royalty Rate
8.9% - 17.9%
Tiered up to 21.9%
Dev Milestones
$514M
Range: $367M - $667M

Market Analysis

RSV is one of the most actively transacted indications in infectious disease licensing. Phase 2 deals for rsv carry a median total deal value of $3.2B, with upfront payments ranging from $481M to $1.1B. The recommended deal structure allocates approximately 26% to upfront payments and 74% to milestones.

Milestone structures for rsv deals allocate $514M to development milestones, $538M to regulatory milestones, and $1.3B to commercial milestones. Royalty rates range from 8.9% to 17.9% at the base tier, with tiered escalation reaching 12.9%-21.9% on peak sales.

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Frequently Asked Questions

What are typical deal terms for rsv licensing?
Phase 2 rsv licensing deals average $826M in upfront payments with $3.2B total deal value. The 26/74 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for rsv deals?
Base royalty rates for rsv transactions range from 8.9% to 17.9%, with tiered escalations reaching 12.9%-21.9% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are rsv deal milestones structured?
RSV deals allocate approximately 74% of total deal value to milestones. Development milestones ($514M) make up the largest share, followed by commercial milestones ($1.3B) and regulatory milestones ($538M).
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