Resistant Hypertension — Deal Benchmarks & Valuation
Market Analysis
Resistant Hypertension is one of the most actively transacted indications in cardiovascular licensing. Phase 2 deals for resistant hypertension carry a median total deal value of $3.0B, with upfront payments ranging from $330M to $874M. The recommended deal structure allocates approximately 20% to upfront payments and 80% to milestones.
Milestone structures for resistant hypertension deals allocate $537M to development milestones, $684M to regulatory milestones, and $1.2B to commercial milestones. Royalty rates range from 9.4% to 18.7% at the base tier, with tiered escalation reaching 13.4%-22.7% on peak sales.
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