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NASH (GI) — Deal Benchmarks & Valuation

Median Upfront
$552M
Range: $295M - $799M
Total Deal Value
$2.8B
Range: $1.8B - $3.9B
Royalty Rate
7.8% - 14.4%
Tiered up to 18.4%
Dev Milestones
$475M
Range: $310M - $641M

Market Analysis

NASH (GI) is one of the most actively transacted indications in gastroenterology licensing. Phase 2 deals for nash (gi) carry a median total deal value of $2.8B, with upfront payments ranging from $295M to $799M. The recommended deal structure allocates approximately 20% to upfront payments and 80% to milestones.

Milestone structures for nash (gi) deals allocate $475M to development milestones, $565M to regulatory milestones, and $1.2B to commercial milestones. Royalty rates range from 7.8% to 14.4% at the base tier, with tiered escalation reaching 11.8%-18.4% on peak sales.

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Frequently Asked Questions

What are typical deal terms for nash (gi) licensing?
Phase 2 nash (gi) licensing deals average $552M in upfront payments with $2.8B total deal value. The 20/80 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for nash (gi) deals?
Base royalty rates for nash (gi) transactions range from 7.8% to 14.4%, with tiered escalations reaching 11.8%-18.4% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are nash (gi) deal milestones structured?
NASH (GI) deals allocate approximately 80% of total deal value to milestones. Development milestones ($475M) make up the largest share, followed by commercial milestones ($1.2B) and regulatory milestones ($565M).
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