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IBS-D — Deal Benchmarks & Valuation

Median Upfront
$381M
Range: $203M - $551M
Total Deal Value
$1.9B
Range: $1.2B - $2.7B
Royalty Rate
6.9% - 12.9%
Tiered up to 16.9%
Dev Milestones
$327M
Range: $214M - $442M

Market Analysis

IBS-D is one of the most actively transacted indications in gastroenterology licensing. Phase 2 deals for ibs-d carry a median total deal value of $1.9B, with upfront payments ranging from $203M to $551M. The recommended deal structure allocates approximately 20% to upfront payments and 80% to milestones.

Milestone structures for ibs-d deals allocate $327M to development milestones, $390M to regulatory milestones, and $841M to commercial milestones. Royalty rates range from 6.9% to 12.9% at the base tier, with tiered escalation reaching 10.9%-16.9% on peak sales.

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Frequently Asked Questions

What are typical deal terms for ibs-d licensing?
Phase 2 ibs-d licensing deals average $381M in upfront payments with $1.9B total deal value. The 20/80 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for ibs-d deals?
Base royalty rates for ibs-d transactions range from 6.9% to 12.9%, with tiered escalations reaching 10.9%-16.9% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are ibs-d deal milestones structured?
IBS-D deals allocate approximately 80% of total deal value to milestones. Development milestones ($327M) make up the largest share, followed by commercial milestones ($841M) and regulatory milestones ($390M).
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