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Myopia Progression — Deal Benchmarks & Valuation

Median Upfront
$461M
Range: $254M - $659M
Total Deal Value
$2.2B
Range: $1.4B - $2.9B
Royalty Rate
8.8% - 17.5%
Tiered up to 21.5%
Dev Milestones
$342M
Range: $231M - $454M

Market Analysis

Myopia Progression is one of the most actively transacted indications in ophthalmology licensing. Phase 2 deals for myopia progression carry a median total deal value of $2.2B, with upfront payments ranging from $254M to $659M. The recommended deal structure allocates approximately 21% to upfront payments and 79% to milestones.

Milestone structures for myopia progression deals allocate $342M to development milestones, $428M to regulatory milestones, and $941M to commercial milestones. Royalty rates range from 8.8% to 17.5% at the base tier, with tiered escalation reaching 12.8%-21.5% on peak sales.

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Frequently Asked Questions

What are typical deal terms for myopia progression licensing?
Phase 2 myopia progression licensing deals average $461M in upfront payments with $2.2B total deal value. The 21/79 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for myopia progression deals?
Base royalty rates for myopia progression transactions range from 8.8% to 17.5%, with tiered escalations reaching 12.8%-21.5% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are myopia progression deal milestones structured?
Myopia Progression deals allocate approximately 79% of total deal value to milestones. Development milestones ($342M) make up the largest share, followed by commercial milestones ($941M) and regulatory milestones ($428M).
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