Diabetic Macular Edema — Deal Benchmarks & Valuation
Market Analysis
Diabetic Macular Edema is one of the most actively transacted indications in ophthalmology licensing. Phase 2 deals for diabetic macular edema carry a median total deal value of $3.5B, with upfront payments ranging from $406M to $1.1B. The recommended deal structure allocates approximately 21% to upfront payments and 79% to milestones.
Milestone structures for diabetic macular edema deals allocate $546M to development milestones, $683M to regulatory milestones, and $1.5B to commercial milestones. Royalty rates range from 10.1% to 20.2% at the base tier, with tiered escalation reaching 14.1%-24.2% on peak sales.
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Frequently Asked Questions
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