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Uterine Fibroids — Deal Benchmarks & Valuation

Median Upfront
$317M
Range: $165M - $467M
Total Deal Value
$1.7B
Range: $1.1B - $2.4B
Royalty Rate
7.8% - 15.6%
Tiered up to 19.6%
Dev Milestones
$312M
Range: $200M - $424M

Market Analysis

Uterine Fibroids is one of the most actively transacted indications in women's health licensing. Phase 2 deals for uterine fibroids carry a median total deal value of $1.7B, with upfront payments ranging from $165M to $467M. The recommended deal structure allocates approximately 18% to upfront payments and 82% to milestones.

Milestone structures for uterine fibroids deals allocate $312M to development milestones, $326M to regulatory milestones, and $780M to commercial milestones. Royalty rates range from 7.8% to 15.6% at the base tier, with tiered escalation reaching 11.8%-19.6% on peak sales.

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Frequently Asked Questions

What are typical deal terms for uterine fibroids licensing?
Phase 2 uterine fibroids licensing deals average $317M in upfront payments with $1.7B total deal value. The 18/82 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for uterine fibroids deals?
Base royalty rates for uterine fibroids transactions range from 7.8% to 15.6%, with tiered escalations reaching 11.8%-19.6% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are uterine fibroids deal milestones structured?
Uterine Fibroids deals allocate approximately 82% of total deal value to milestones. Development milestones ($312M) make up the largest share, followed by commercial milestones ($780M) and regulatory milestones ($326M).
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