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PTSD — Deal Benchmarks & Valuation

Median Upfront
$357M
Range: $177M - $539M
Total Deal Value
$3.2B
Range: $1.9B - $4.4B
Royalty Rate
12.5% - 20%
Tiered up to 24%
Dev Milestones
$924M
Range: $567M - $1.3B

Market Analysis

PTSD is one of the most actively transacted indications in neurology licensing. Phase 2 deals for ptsd carry a median total deal value of $3.2B, with upfront payments ranging from $177M to $539M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.

Milestone structures for ptsd deals allocate $924M to development milestones, $1.0B to regulatory milestones, and $868M to commercial milestones. Royalty rates range from 12.5% to 20% at the base tier, with tiered escalation reaching 16.5%-24% on peak sales.

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Frequently Asked Questions

What are typical deal terms for ptsd licensing?
Phase 2 ptsd licensing deals average $357M in upfront payments with $3.2B total deal value. The 11/89 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for ptsd deals?
Base royalty rates for ptsd transactions range from 12.5% to 20%, with tiered escalations reaching 16.5%-24% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are ptsd deal milestones structured?
PTSD deals allocate approximately 89% of total deal value to milestones. Development milestones ($924M) make up the largest share, followed by commercial milestones ($868M) and regulatory milestones ($1.0B).
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