Skip to main content

Phenylketonuria (PKU) — Deal Benchmarks & Valuation

Median Upfront
$239M
Range: $111M - $367M
Total Deal Value
$1.9B
Range: $1.0B - $2.7B
Royalty Rate
9.4% - 17.6%
Tiered up to 21.6%
Dev Milestones
$493M
Range: $278M - $709M

Market Analysis

Phenylketonuria (PKU) is one of the most actively transacted indications in metabolic licensing. Phase 1 deals for phenylketonuria (pku) carry a median total deal value of $1.9B, with upfront payments ranging from $111M to $367M. The recommended deal structure allocates approximately 13% to upfront payments and 87% to milestones.

PRO

Full Benchmark Analysis

Complete deal term ranges, comparable transactions, and negotiation insights.

We'll email you the full benchmark data for this page. No spam, unsubscribe anytime.

or
Unlock Everything — $299/mo Pro

7-day money-back guarantee · Cancel anytime

Customize these benchmarks for your asset

Adjust phase, modality, competitive position, and 10+ other parameters.

Open Calculator

Frequently Asked Questions

What are typical deal terms for phenylketonuria (pku) licensing?
Phase 1 phenylketonuria (pku) licensing deals average $239M in upfront payments with $1.9B total deal value. The 13/87 upfront/milestone split reflects the risk profile at this clinical stage.
PRO

Full Benchmark Analysis

Complete deal term ranges, comparable transactions, and negotiation insights.

We'll email you the full benchmark data for this page. No spam, unsubscribe anytime.

or
Unlock Everything — $299/mo Pro

7-day money-back guarantee · Cancel anytime

Ready to Calculate Your Deal Terms?

Get instant, customized benchmarks based on real market data from 1,600+ biopharma licensing deals.

Start Calculating
For Funds & Advisors

Need the full deal landscape?

The Deal Intelligence Brief covers every modality and deal structure for this indication — 52 deal calculations, AI strategic narrative, comparable transactions, partner matching, and white-label branding. Delivered in 24 hours.

Configure Brief — $2,500All-inclusive · White-label · Walkthrough included