Chronic / Neuropathic Pain — Deal Benchmarks & Valuation
Market Analysis
Chronic / Neuropathic Pain is one of the most actively transacted indications in neurology licensing. Phase 2 deals for chronic / neuropathic pain carry a median total deal value of $2.4B, with upfront payments ranging from $135M to $410M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.
Milestone structures for chronic / neuropathic pain deals allocate $703M to development milestones, $766M to regulatory milestones, and $660M to commercial milestones. Royalty rates range from 11.5% to 18.4% at the base tier, with tiered escalation reaching 15.5%-22.4% on peak sales.
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Frequently Asked Questions
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