Narcolepsy — Deal Benchmarks & Valuation
Market Analysis
Narcolepsy is one of the most actively transacted indications in neurology licensing. Phase 2 deals for narcolepsy carry a median total deal value of $2.7B, with upfront payments ranging from $153M to $465M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.
Milestone structures for narcolepsy deals allocate $797M to development milestones, $869M to regulatory milestones, and $748M to commercial milestones. Royalty rates range from 12% to 19.1% at the base tier, with tiered escalation reaching 16%-23.1% on peak sales.
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