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Myotonic Dystrophy — Deal Benchmarks & Valuation

Median Upfront
$134M
Range: $54M - $223M
Total Deal Value
$2.0B
Range: $990M - $3.0B
Royalty Rate
7.9% - 15.7%
Tiered up to 19.7%
Dev Milestones
$923M
Range: $468M - $1.4B

Market Analysis

Myotonic Dystrophy is one of the most actively transacted indications in neurology licensing. Phase 1 deals for myotonic dystrophy carry a median total deal value of $2.0B, with upfront payments ranging from $54M to $223M. The recommended deal structure allocates approximately 7% to upfront payments and 93% to milestones.

Milestone structures for myotonic dystrophy deals allocate $923M to development milestones, $554M to regulatory milestones, and $369M to commercial milestones. Royalty rates range from 7.9% to 15.7% at the base tier, with tiered escalation reaching 11.9%-19.7% on peak sales.

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Frequently Asked Questions

What are typical deal terms for myotonic dystrophy licensing?
Phase 1 myotonic dystrophy licensing deals average $134M in upfront payments with $2.0B total deal value. The 7/93 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for myotonic dystrophy deals?
Base royalty rates for myotonic dystrophy transactions range from 7.9% to 15.7%, with tiered escalations reaching 11.9%-19.7% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are myotonic dystrophy deal milestones structured?
Myotonic Dystrophy deals allocate approximately 93% of total deal value to milestones. Development milestones ($923M) make up the largest share, followed by commercial milestones ($369M) and regulatory milestones ($554M).
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