Myelofibrosis — Deal Benchmarks & Valuation
Market Analysis
Myelofibrosis is one of the most actively transacted indications in hematology licensing. Phase 2 deals for myelofibrosis carry a median total deal value of $3.1B, with upfront payments ranging from $333M to $932M. The recommended deal structure allocates approximately 20% to upfront payments and 80% to milestones.
Milestone structures for myelofibrosis deals allocate $526M to development milestones, $626M to regulatory milestones, and $1.4B to commercial milestones. Royalty rates range from 8.7% to 16.3% at the base tier, with tiered escalation reaching 12.7%-20.3% on peak sales.
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Frequently Asked Questions
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