Multiple Sclerosis — Deal Benchmarks & Valuation
Market Analysis
Multiple Sclerosis is one of the most actively transacted indications in neurology licensing. Phase 2 deals for multiple sclerosis carry a median total deal value of $2.3B, with upfront payments ranging from $129M to $391M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.
Milestone structures for multiple sclerosis deals allocate $671M to development milestones, $732M to regulatory milestones, and $630M to commercial milestones. Royalty rates range from 11.4% to 18.2% at the base tier, with tiered escalation reaching 15.4%-22.2% on peak sales.
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Frequently Asked Questions
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