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Huntington's Disease (Rare) — Deal Benchmarks & Valuation

Median Upfront
$140M
Range: $55M - $232M
Total Deal Value
$1.3B
Range: $609M - $1.9B
Royalty Rate
5.8% - 11.6%
Tiered up to 15.6%
Dev Milestones
$395M
Range: $194M - $593M

Market Analysis

Huntington's Disease (Rare) is one of the most actively transacted indications in rare disease licensing. Phase 1 deals for huntington's disease (rare) carry a median total deal value of $1.3B, with upfront payments ranging from $55M to $232M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.

Milestone structures for huntington's disease (rare) deals allocate $395M to development milestones, $305M to regulatory milestones, and $429M to commercial milestones. Royalty rates range from 5.8% to 11.6% at the base tier, with tiered escalation reaching 9.8%-15.6% on peak sales.

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Frequently Asked Questions

What are typical deal terms for huntington's disease (rare) licensing?
Phase 1 huntington's disease (rare) licensing deals average $140M in upfront payments with $1.3B total deal value. The 11/89 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for huntington's disease (rare) deals?
Base royalty rates for huntington's disease (rare) transactions range from 5.8% to 11.6%, with tiered escalations reaching 9.8%-15.6% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are huntington's disease (rare) deal milestones structured?
Huntington's Disease (Rare) deals allocate approximately 89% of total deal value to milestones. Development milestones ($395M) make up the largest share, followed by commercial milestones ($429M) and regulatory milestones ($305M).
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