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Frontotemporal Dementia (FTD) — Deal Benchmarks & Valuation

Median Upfront
$111M
Range: $45M - $184M
Total Deal Value
$1.6B
Range: $806M - $2.4B
Royalty Rate
7.4% - 14.8%
Tiered up to 18.8%
Dev Milestones
$750M
Range: $381M - $1.1B

Market Analysis

Frontotemporal Dementia (FTD) is one of the most actively transacted indications in neurology licensing. Phase 1 deals for frontotemporal dementia (ftd) carry a median total deal value of $1.6B, with upfront payments ranging from $45M to $184M. The recommended deal structure allocates approximately 7% to upfront payments and 93% to milestones.

Milestone structures for frontotemporal dementia (ftd) deals allocate $750M to development milestones, $450M to regulatory milestones, and $300M to commercial milestones. Royalty rates range from 7.4% to 14.8% at the base tier, with tiered escalation reaching 11.4%-18.8% on peak sales.

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Frequently Asked Questions

What are typical deal terms for frontotemporal dementia (ftd) licensing?
Phase 1 frontotemporal dementia (ftd) licensing deals average $111M in upfront payments with $1.6B total deal value. The 7/93 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for frontotemporal dementia (ftd) deals?
Base royalty rates for frontotemporal dementia (ftd) transactions range from 7.4% to 14.8%, with tiered escalations reaching 11.4%-18.8% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are frontotemporal dementia (ftd) deal milestones structured?
Frontotemporal Dementia (FTD) deals allocate approximately 93% of total deal value to milestones. Development milestones ($750M) make up the largest share, followed by commercial milestones ($300M) and regulatory milestones ($450M).
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