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Friedreich's Ataxia — Deal Benchmarks & Valuation

Median Upfront
$117M
Range: $47M - $194M
Total Deal Value
$1.7B
Range: $862M - $2.6B
Royalty Rate
7.6% - 15.1%
Tiered up to 19.1%
Dev Milestones
$803M
Range: $408M - $1.2B

Market Analysis

Friedreich's Ataxia is one of the most actively transacted indications in neurology licensing. Phase 1 deals for friedreich's ataxia carry a median total deal value of $1.7B, with upfront payments ranging from $47M to $194M. The recommended deal structure allocates approximately 7% to upfront payments and 93% to milestones.

Milestone structures for friedreich's ataxia deals allocate $803M to development milestones, $482M to regulatory milestones, and $321M to commercial milestones. Royalty rates range from 7.6% to 15.1% at the base tier, with tiered escalation reaching 11.6%-19.1% on peak sales.

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Frequently Asked Questions

What are typical deal terms for friedreich's ataxia licensing?
Phase 1 friedreich's ataxia licensing deals average $117M in upfront payments with $1.7B total deal value. The 7/93 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for friedreich's ataxia deals?
Base royalty rates for friedreich's ataxia transactions range from 7.6% to 15.1%, with tiered escalations reaching 11.6%-19.1% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are friedreich's ataxia deal milestones structured?
Friedreich's Ataxia deals allocate approximately 93% of total deal value to milestones. Development milestones ($803M) make up the largest share, followed by commercial milestones ($321M) and regulatory milestones ($482M).
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