Fabry Disease — Deal Benchmarks & Valuation
Market Analysis
Fabry Disease is one of the most actively transacted indications in rare disease licensing. Phase 2 deals for fabry disease carry a median total deal value of $2.3B, with upfront payments ranging from $212M to $651M. The recommended deal structure allocates approximately 19% to upfront payments and 81% to milestones.
Milestone structures for fabry disease deals allocate $417M to development milestones, $474M to regulatory milestones, and $1.0B to commercial milestones. Royalty rates range from 7.8% to 15.6% at the base tier, with tiered escalation reaching 11.8%-19.6% on peak sales.
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Frequently Asked Questions
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