Epilepsy — Deal Benchmarks & Valuation
Market Analysis
Epilepsy is one of the most actively transacted indications in neurology licensing. Phase 2 deals for epilepsy carry a median total deal value of $2.7B, with upfront payments ranging from $149M to $454M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.
Milestone structures for epilepsy deals allocate $778M to development milestones, $849M to regulatory milestones, and $731M to commercial milestones. Royalty rates range from 11.9% to 19% at the base tier, with tiered escalation reaching 15.9%-23% on peak sales.
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