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Autism Spectrum Disorder — Deal Benchmarks & Valuation

Median Upfront
$324M
Range: $161M - $490M
Total Deal Value
$2.9B
Range: $1.7B - $4.0B
Royalty Rate
12.1% - 19.4%
Tiered up to 23.4%
Dev Milestones
$840M
Range: $515M - $1.2B

Market Analysis

Autism Spectrum Disorder is one of the most actively transacted indications in neurology licensing. Phase 2 deals for autism spectrum disorder carry a median total deal value of $2.9B, with upfront payments ranging from $161M to $490M. The recommended deal structure allocates approximately 11% to upfront payments and 89% to milestones.

Milestone structures for autism spectrum disorder deals allocate $840M to development milestones, $917M to regulatory milestones, and $789M to commercial milestones. Royalty rates range from 12.1% to 19.4% at the base tier, with tiered escalation reaching 16.1%-23.4% on peak sales.

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Frequently Asked Questions

What are typical deal terms for autism spectrum disorder licensing?
Phase 2 autism spectrum disorder licensing deals average $324M in upfront payments with $2.9B total deal value. The 11/89 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for autism spectrum disorder deals?
Base royalty rates for autism spectrum disorder transactions range from 12.1% to 19.4%, with tiered escalations reaching 16.1%-23.4% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are autism spectrum disorder deal milestones structured?
Autism Spectrum Disorder deals allocate approximately 89% of total deal value to milestones. Development milestones ($840M) make up the largest share, followed by commercial milestones ($789M) and regulatory milestones ($917M).
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