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Dermatology Deal Benchmarks

Benchmark licensing terms for atopic dermatitis, psoriasis, vitiligo, alopecia areata, and other skin conditions. Dermatology deals benefit from large patient populations and growing biologic adoption. Benchmarks derived from 184 verified transactions.

184
Total Deals
$157M
Avg Upfront
5
Deal Types
100%
Terms Disclosed

Deal Structure Distribution

107
license
49
acquisition
17
collaboration
10
option
1
co development

Recent Deals with Disclosed Terms

PartiesTypeUpfrontTotal ValueDate
Junshi Biosciences → Fosun Pharma
roconkibart (JS005)
license$30M$186MJul 2026
Ascendant Health / Genesis Life Sciences → Cue Biopharma
Ascendant-221 / CUE-221
license$15M$692MApr 2026
Replay → Leo Pharma
skin disease gene therapy
license$50M$50MApr 2026
Boehringer Ingelheim → AbbVie
BI 655066
license$595M—Mar 2026
Teva Pharmaceuticals → Royalty Pharma
TEV-53408
license$75M$500MJan 2026
Royalty Pharma → Teva
TEV-'408
co development$75M$500MJan 2026
Hatchtech Pty Ltd → Pelthos Therapeutics Inc.
Xeglyze
acquisition$2M$2MDec 2025
Acera Surgical → Solventum
wound care products
acquisition$725M$850MNov 2025
Biofrontera Inc. / Ferrer Internacional S.A. → Pelthos Therapeutics, Inc.
Xepi (ozenoxacin) Cream, 1%
acquisition$4M$11MNov 2025
Acrux Limited → Servacure Trading W.L.L.
Dapsone 5%, Gel
license$1M$5MJul 2025

Benchmark Your Dermatology Deal

Get instant benchmarks for upfront payments, milestones, and royalties based on 184 verified dermatology transactions.

Dermatology Deal Benchmarking FAQ

How are atopic dermatitis deal valuations trending in 2026?
Atopic dermatitis remains the highest-value dermatology indication for deal-making, driven by the validated dupilumab franchise and competition among next-gen IL-13, IL-31, and OX40 approaches. Clinical-stage AD assets command upfronts of $50M-$200M+ with total deal values exceeding $1B for differentiated mechanisms.
What deal structures are common in dermatology licensing?
Dermatology deals frequently use geographic licensing structures, with licensors retaining North America and out-licensing ex-US rights. Co-promotion agreements are also common for launched products. Upfronts range $20M-$150M depending on indication breadth and stage, with royalties of 10-20% on net sales.
How do topical vs systemic dermatology deals compare?
Systemic dermatology deals (biologics, oral JAK inhibitors) command significantly higher valuations than topical deals, reflecting larger commercial potential. Topical deals typically feature lower upfronts ($5M-$30M) and royalties (5-12%), while systemic biologic deals for psoriasis and AD are benchmarked alongside immunology transactions.