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Pfizer

Pays vs peer median
×1.50
+50% premium
Sample
18
high confidence
Last refreshed
2026-04-13

By therapeutic area

Therapeutic areaPremiumDeals
oncology×1.504
infectiousDisease×1.504
gastroenterology×1.503

By stage at signing

PhasePremiumDeals
approved×1.506
phase 1×1.164
phase 2×1.504

Strategy profile

Based on 15 disclosed transactions, Pfizer concentrates its licensing activity in InfectiousDisease, Gastroenterology, and Oncology. Pfizer pays a 1.50x premium over market median, with the strongest premiums in Oncology (1.50x). Their most common deal structure is Acquisition, with an average disclosed value of $5.9B. Most recent activity: 2025.

Premium by therapeutic area

How Pfizer pays relative to peer medians in each TA

oncology
4 deals1.50x
gastroenterology
3 deals1.50x
infectiousDisease
4 deals1.50x
Above market (≥1.10x)At market (0.90 – 1.10x)Below market (<0.90x)

Pipeline coverage & gaps

Pfizer has disclosed activity in 3 of 12 tracked therapeutic areas. Gaps may represent whitespace opportunities for licensors.

Oncology
1.50x
4 deals
Neurology
Gap
No disclosed deals
Immunology
Gap
No disclosed deals
Metabolic
Gap
No disclosed deals
Cardiovascular
Gap
No disclosed deals
Infectious Disease
1.50x
4 deals
Ophthalmology
Gap
No disclosed deals
Womens Health
Gap
No disclosed deals
Rare Disease
Gap
No disclosed deals
Hematology
Gap
No disclosed deals
Dermatology
Gap
No disclosed deals
Gastroenterology
1.50x
3 deals

Deal type breakdown

How this buyer structures its transactions

Deal typeCountAvg upfrontAvg total value
AcquisitionPrimary6$11.6B$11.6B
License4$500M$3.5B
Collaboration3$178M$1.3B
Option1$50M$800M
Co Promotion1$75M$300M

Recent disclosed deals

YearAssetLicensorIndicationPhaseUpfrontTotal
2025S3Bio asset (exclusive license)S3Biounknown$6.1B
2025SSGJ-707 / PF-086344043SBio / Sunshine Guojianmultiple solid tumors including NSCLC, small cell lung cancer, gastric cancer, colorectal cancerphase_3$1.3B$6.3B
2024ulcerativeColitisIterative HealthulcerativeColitisapproved$160M$1.6B
2023breast_her2Seagenbreast_her2approved$43.0B$43.0B
2023covidArvinascovidpreclinical$75M$800M
2023crohnsTheravance Biopharmacrohnsphase_2$100M$900M
2023atopicdermEvommuneatopicdermphase_1$50M$800M
2023CefiderocolShionogiMDR gram-negative infectionsapproved$75M$300M
2022ulcerativeColitisArena PharmaceuticalsulcerativeColitisphase_3$6.7B$6.7B
2022sickleCellGlobal Blood TherapeuticssickleCellapproved$5.4B$5.4B
2022migraineBiohaven Pharmaceuticalmigraineapproved$11.6B$11.6B
2022covidShionogicovidapproved$150M$800M
2022SisunatovirReViralRSVphase_2$525M$525M
2022Base editing programsBeam TherapeuticsRare Hematologic and Hepatic Diseasespreclinical$300M$1.4B
2021TTI-622 and TTI-621Trillium TherapeuticsAML, MDSphase_1$2.3B$2.3B

How this is computed

For each Pfizer deal we find the median total deal value of comparable transactions (same therapeutic area + phase, falling back to TA-only with ≥3 peers). The buyer’s deal divided by the peer median is the per-deal premium. We trim outliers, take the trimmed mean, and clamp to [0.7×, 1.5×] to reject data errors. Confidence scales with sample size.

Trimmed mean of 18 disclosed deal premiums vs. peer medians. Raw premium 1.939, clamped to [0.7, 1.5].