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Biogen

Pays vs peer median
×1.27
+27% premium
Sample
30
high confidence
Last refreshed
2026-04-13

By therapeutic area

Therapeutic areaPremiumDeals
oncology×1.1517
neurology×1.506
rareDisease×1.154

By stage at signing

PhasePremiumDeals
approved×1.508
phase 1×1.167
phase 3×1.157
preclinical×1.324
phase 2×0.703

Strategy profile

Based on 15 disclosed transactions, Biogen concentrates its licensing activity in Immunology, Neurology, and Oncology. Biogen pays a 1.27x premium over market median, with the strongest premiums in Neurology (1.50x). Their most common deal structure is Acquisition, with an average disclosed value of $1.7B. Most recent activity: 2026.

Premium by therapeutic area

How Biogen pays relative to peer medians in each TA

neurology
6 deals1.50x
oncology
17 deals1.15x
rareDisease
4 deals1.15x
Above market (≥1.10x)At market (0.90 – 1.10x)Below market (<0.90x)

Pipeline coverage & gaps

Biogen has disclosed activity in 3 of 12 tracked therapeutic areas. Gaps may represent whitespace opportunities for licensors.

Oncology
1.15x
17 deals
Neurology
1.50x
6 deals
Immunology
Gap
No disclosed deals
Metabolic
Gap
No disclosed deals
Cardiovascular
Gap
No disclosed deals
Infectious Disease
Gap
No disclosed deals
Ophthalmology
Gap
No disclosed deals
Womens Health
Gap
No disclosed deals
Rare Disease
1.15x
4 deals
Hematology
Gap
No disclosed deals
Dermatology
Gap
No disclosed deals
Gastroenterology
Gap
No disclosed deals

Deal type breakdown

How this buyer structures its transactions

Deal typeCountAvg upfrontAvg total value
AcquisitionPrimary8$2.1B$2.7B
License3$77M$725M
Collaboration2$518M
Option1$27M$529M
Co Development1$27M$297M

Recent disclosed deals

YearAssetLicensorIndicationPhaseUpfrontTotal
2026Empaveli / SyfovreApellis Pharmaceuticalsrare kidney/blood diseases and macular degenerationapproved$5.6B$5.6B
2026not disclosedRayTherainflammatory diseasespreclinical$1.0B
2026felzartamabTJ BiopharmaIgA nephropathy, primary membranous nephropathy, antibody-mediated rejection in kidney transplant recipients, multiple myelomaphase_3$100M$850M
2026Syfovre + Empaveli (full company acquisition)Apellis Pharmaceuticalscomplement_c3gapproved$5.6B$6.0B
2026EMPAVELI and SYFOVREApellisimmunology, rare disease, ophthalmology, and nephrologyunknown$5.6B
2026ALT-B4Alteogen Inc.unknown$20M$579M
2025ThecaFlex DRxAlcyone Therapeuticsneurological disordersunknown$85M$85M
2025litifilimabRoyalty Pharmasystemic lupus erythematosus and cutaneous lupus erythematosusphase_3$250M
2025RNAi-based CNS therapiesCity TherapeuticsCNS diseasesdiscovery$46M$1.0B
2025Zorevunersen (Dravet syndrome)Stoke TherapeuticsDravet syndromephase_2$165M$550M
2025CD20Zai LabPancreaticphase_1$786M
2024TGF-β-001Umoja BiopharmaGastricpreclinical$95M$856M
2024MDM2Chugai PharmaceuticalBreast (HR+)discovery$27M$529M
2024FRα-tinibZymeworksHead & Neckdiscovery$27M$297M
2024autoimmuneHI-Bioautoimmunephase_2$1.1B$1.8B

How this is computed

For each Biogen deal we find the median total deal value of comparable transactions (same therapeutic area + phase, falling back to TA-only with ≥3 peers). The buyer’s deal divided by the peer median is the per-deal premium. We trim outliers, take the trimmed mean, and clamp to [0.7×, 1.5×] to reject data errors. Confidence scales with sample size.

Trimmed mean of 30 disclosed deal premiums vs. peer medians. Raw premium 1.274, clamped to [0.7, 1.5].