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Alexion

Pays vs peer median
×0.89
-11% premium
Sample
3
low confidence
Last refreshed
2026-07-01

By therapeutic area

Therapeutic areaPremiumDeals
rareDisease×0.893

By stage at signing

Not enough phase-specific data (need ≥3 deals per phase).

Strategy profile

Based on 3 disclosed transactions, Alexion concentrates its licensing activity in RareDisease. Alexion pays a 0.89x discount to market median, with the strongest premiums in RareDisease (0.89x). Their most common deal structure is Acquisition, with an average disclosed value of $1.2B. Most recent activity: 2020.

Premium by therapeutic area

How Alexion pays relative to peer medians in each TA

rareDisease
3 deals0.89x
Above market (≥1.10x)At market (0.90 – 1.10x)Below market (<0.90x)

Pipeline coverage & gaps

Alexion has disclosed activity in 1 of 12 tracked therapeutic areas. Gaps may represent whitespace opportunities for licensors.

Oncology
Gap
No disclosed deals
Neurology
Gap
No disclosed deals
Immunology
Gap
No disclosed deals
Metabolic
Gap
No disclosed deals
Cardiovascular
Gap
No disclosed deals
Infectious Disease
Gap
No disclosed deals
Ophthalmology
Gap
No disclosed deals
Womens Health
Gap
No disclosed deals
Rare Disease
0.89x
3 deals
Hematology
Gap
No disclosed deals
Dermatology
Gap
No disclosed deals
Gastroenterology
Gap
No disclosed deals

Deal type breakdown

How this buyer structures its transactions

Deal typeCountAvg upfrontAvg total value
AcquisitionPrimary3$913M$1.2B

Recent disclosed deals

YearAssetLicensorIndicationPhaseUpfrontTotal
2020Andexanet alfa (Andexxa)Portola PharmaceuticalsReversal of Factor Xa Inhibitorsapproved$1.4B$1.4B
2019Danicopan (Factor D inhibitor)Achillion PharmaceuticalsParoxysmal Nocturnal Hemoglobinuriaphase_2$930M$930M
2018SYNT001 (anti-FcRn)SyntimmuneWarm Autoimmune Hemolytic Anemiaphase_1$400M$1.2B

How this is computed

For each Alexion deal we find the median total deal value of comparable transactions (same therapeutic area + phase, falling back to TA-only with ≥3 peers). The buyer’s deal divided by the peer median is the per-deal premium. We trim outliers, take the trimmed mean, and clamp to [0.7×, 1.5×] to reject data errors. Confidence scales with sample size.

Trimmed mean of 3 disclosed deal premiums vs. peer medians. Raw premium 0.892, clamped to [0.7, 1.5].