Systemic Sclerosis — Deal Benchmarks & Valuation
Market Analysis
Systemic Sclerosis is one of the most actively transacted indications in immunology licensing. Phase 2 deals for systemic sclerosis carry a median total deal value of $3.0B, with upfront payments ranging from $302M to $824M. The recommended deal structure allocates approximately 19% to upfront payments and 81% to milestones.
Milestone structures for systemic sclerosis deals allocate $479M to development milestones, $839M to regulatory milestones, and $1.1B to commercial milestones. Royalty rates range from 13.9% to 23.2% at the base tier, with tiered escalation reaching 17.9%-27.2% on peak sales.
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Frequently Asked Questions
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