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Renal Cell Carcinoma (RCC) — Deal Benchmarks & Valuation

Median Upfront
$226M
Range: $126M - $320M
Total Deal Value
$1.4B
Range: $935M - $1.9B
Royalty Rate
11.3% - 18.6%
Tiered up to 22.6%
Dev Milestones
$303M
Range: $202M - $405M

Market Analysis

Renal Cell Carcinoma (RCC) is one of the most actively transacted indications in oncology licensing. Phase 2 deals for renal cell carcinoma (rcc) carry a median total deal value of $1.4B, with upfront payments ranging from $126M to $320M. The recommended deal structure allocates approximately 16% to upfront payments and 84% to milestones.

Milestone structures for renal cell carcinoma (rcc) deals allocate $303M to development milestones, $485M to regulatory milestones, and $424M to commercial milestones. Royalty rates range from 11.3% to 18.6% at the base tier, with tiered escalation reaching 15.3%-22.6% on peak sales.

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Frequently Asked Questions

What are typical deal terms for renal cell carcinoma (rcc) licensing?
Phase 2 renal cell carcinoma (rcc) licensing deals average $226M in upfront payments with $1.4B total deal value. The 16/84 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for renal cell carcinoma (rcc) deals?
Base royalty rates for renal cell carcinoma (rcc) transactions range from 11.3% to 18.6%, with tiered escalations reaching 15.3%-22.6% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are renal cell carcinoma (rcc) deal milestones structured?
Renal Cell Carcinoma (RCC) deals allocate approximately 84% of total deal value to milestones. Development milestones ($303M) make up the largest share, followed by commercial milestones ($424M) and regulatory milestones ($485M).
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