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Myasthenia Gravis — Deal Benchmarks & Valuation

Median Upfront
$801M
Range: $425M - $1.2B
Total Deal Value
$4.2B
Range: $2.6B - $5.8B
Royalty Rate
15.4% - 25.7%
Tiered up to 29.7%
Dev Milestones
$675M
Range: $433M - $921M

Market Analysis

Myasthenia Gravis is one of the most actively transacted indications in immunology licensing. Phase 2 deals for myasthenia gravis carry a median total deal value of $4.2B, with upfront payments ranging from $425M to $1.2B. The recommended deal structure allocates approximately 19% to upfront payments and 81% to milestones.

Milestone structures for myasthenia gravis deals allocate $675M to development milestones, $1.2B to regulatory milestones, and $1.5B to commercial milestones. Royalty rates range from 15.4% to 25.7% at the base tier, with tiered escalation reaching 19.4%-29.7% on peak sales.

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Frequently Asked Questions

What are typical deal terms for myasthenia gravis licensing?
Phase 2 myasthenia gravis licensing deals average $801M in upfront payments with $4.2B total deal value. The 19/81 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for myasthenia gravis deals?
Base royalty rates for myasthenia gravis transactions range from 15.4% to 25.7%, with tiered escalations reaching 19.4%-29.7% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are myasthenia gravis deal milestones structured?
Myasthenia Gravis deals allocate approximately 81% of total deal value to milestones. Development milestones ($675M) make up the largest share, followed by commercial milestones ($1.5B) and regulatory milestones ($1.2B).
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