Melanoma — Deal Benchmarks & Valuation
Market Analysis
Melanoma is one of the most actively transacted indications in oncology licensing. Phase 2 deals for melanoma carry a median total deal value of $1.6B, with upfront payments ranging from $136M to $346M. The recommended deal structure allocates approximately 16% to upfront payments and 84% to milestones.
Milestone structures for melanoma deals allocate $327M to development milestones, $523M to regulatory milestones, and $458M to commercial milestones. Royalty rates range from 11.6% to 19% at the base tier, with tiered escalation reaching 15.6%-23% on peak sales.
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