Skip to main content

HER2-Low Tumors — Deal Benchmarks & Valuation

Median Upfront
$319M
Range: $178M - $451M
Total Deal Value
$2.0B
Range: $1.3B - $2.7B
Royalty Rate
12.6% - 20.6%
Tiered up to 24.6%
Dev Milestones
$427M
Range: $285M - $571M

Market Analysis

HER2-Low Tumors is one of the most actively transacted indications in oncology licensing. Phase 2 deals for her2-low tumors carry a median total deal value of $2.0B, with upfront payments ranging from $178M to $451M. The recommended deal structure allocates approximately 16% to upfront payments and 84% to milestones.

Milestone structures for her2-low tumors deals allocate $427M to development milestones, $682M to regulatory milestones, and $597M to commercial milestones. Royalty rates range from 12.6% to 20.6% at the base tier, with tiered escalation reaching 16.6%-24.6% on peak sales.

Customize these benchmarks for your asset

Adjust phase, modality, competitive position, and 10+ other parameters.

Open Calculator

Frequently Asked Questions

What are typical deal terms for her2-low tumors licensing?
Phase 2 her2-low tumors licensing deals average $319M in upfront payments with $2.0B total deal value. The 16/84 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for her2-low tumors deals?
Base royalty rates for her2-low tumors transactions range from 12.6% to 20.6%, with tiered escalations reaching 16.6%-24.6% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are her2-low tumors deal milestones structured?
HER2-Low Tumors deals allocate approximately 84% of total deal value to milestones. Development milestones ($427M) make up the largest share, followed by commercial milestones ($597M) and regulatory milestones ($682M).
PRO

Full Benchmark Analysis

Complete deal term ranges, comparable transactions, and negotiation insights.

Start 7-Day Free Trial

$299/mo after trial · Cancel anytime

Ready to Calculate Your Deal Terms?

Get instant, customized benchmarks based on real market data from 1,600+ biopharma licensing deals.

Start Calculating
For Funds & Advisors

Need the full deal landscape?

The Deal Intelligence Brief covers every modality and deal structure for this indication — 52 deal calculations, AI strategic narrative, comparable transactions, partner matching, and white-label branding. Delivered in 24 hours.

Configure Brief — $2,500All-inclusive · White-label · Walkthrough included