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Glioblastoma (GBM) — Deal Benchmarks & Valuation

Median Upfront
$142M
Range: $66M - $219M
Total Deal Value
$1.4B
Range: $776M - $2.0B
Royalty Rate
9.9% - 17.3%
Tiered up to 21.3%
Dev Milestones
$508M
Range: $284M - $731M

Market Analysis

Glioblastoma (GBM) is one of the most actively transacted indications in oncology licensing. Phase 1 deals for glioblastoma (gbm) carry a median total deal value of $1.4B, with upfront payments ranging from $66M to $219M. The recommended deal structure allocates approximately 10% to upfront payments and 90% to milestones.

Milestone structures for glioblastoma (gbm) deals allocate $508M to development milestones, $444M to regulatory milestones, and $317M to commercial milestones. Royalty rates range from 9.9% to 17.3% at the base tier, with tiered escalation reaching 13.9%-21.3% on peak sales.

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Frequently Asked Questions

What are typical deal terms for glioblastoma (gbm) licensing?
Phase 1 glioblastoma (gbm) licensing deals average $142M in upfront payments with $1.4B total deal value. The 10/90 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for glioblastoma (gbm) deals?
Base royalty rates for glioblastoma (gbm) transactions range from 9.9% to 17.3%, with tiered escalations reaching 13.9%-21.3% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are glioblastoma (gbm) deal milestones structured?
Glioblastoma (GBM) deals allocate approximately 90% of total deal value to milestones. Development milestones ($508M) make up the largest share, followed by commercial milestones ($317M) and regulatory milestones ($444M).
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