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Cell TherapyPhase 2

Cell Therapy Phase 2 Licensing Benchmarks

Deal economics across 5 transactions with 4 disclosed upfront payments. Primary-source-verified from SEC EDGAR, FTC filings, and direct research.

Median Upfront

$136M

4 deals with terms

Median Total Value

$999M

Upfront + milestones

Royalty Range

9.5%--19%

Average low--high

Deal Count

5

2019--2024

The median upfront payment for phase 2 cell therapy licensing deals is $136M, based on 4 deals with disclosed terms from 2019--2024. Total deal values (including milestones) reach a median of $999M. Royalty rates typically range from 9.5% to 19%. All data is primary-source-verified from SEC EDGAR, FTC pre-merger filings, and company press releases.

Representative Transactions

LicensorLicenseeYearUpfrontTotal Value
Kite PharmaGilead Sciences2019$11.9B$11.9B
ImmaticsBayer2019$158M$1.2B
CRISPR TherapeuticsVertex2022$115M$812.414244M

Showing 3 of 4 deals with disclosed terms. Full comp set available in the report.

Full cell-therapy phase-2 Comp Set

Get the complete analysis -- 4 deals with upfronts, milestones, royalties, and term structures.

Primary-source-verified from SEC EDGAR, FTC filings, and direct research

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Methodology

This analysis draws from the Ambrosia Ventures proprietary deal database (1,600+ verified biopharma transactions, 2019--2024). All deal terms are primary-source-verified from SEC EDGAR (10-K, 10-Q, 8-K filings), FTC pre-merger notifications, FDA Orange Book, and company press releases. No secondary-source or scraped data is included. Medians are calculated from deals with disclosed financial terms only.