Bispecific Antibody Phase 1 Licensing Benchmarks
Deal economics across 27 transactions with 16 disclosed upfront payments. Primary-source-verified from SEC EDGAR, FTC filings, and direct research.
Median Upfront
$194M
16 deals with terms
Median Total Value
$1.1B
Upfront + milestones
Royalty Range
6.6%--14.9%
Average low--high
Deal Count
27
2019--2026
The median upfront payment for phase 1 bispecific antibody licensing deals is $194M, based on 16 deals with disclosed terms from 2019--2026. Total deal values (including milestones) reach a median of $1.1B. Royalty rates typically range from 6.6% to 14.9%. All data is primary-source-verified from SEC EDGAR, FTC pre-merger filings, and company press releases.
Representative Transactions
| Licensor | Licensee | Year | Upfront | Total Value |
|---|---|---|---|---|
| Ouro Medicines | Gilead Sciences | 2026 | $1.7B | $2.2B |
| Ichnos Glenmark Innovation | AbbVie | 2024 | $700M | $1.9B |
| Curon Biopharmaceutical | Merck | 2024 | $700M | $1.3B |
Showing 3 of 16 deals with disclosed terms. Full comp set available in the report.
Full Bispecific Antibody phase-1 Comp Set
Get the complete analysis -- 16 deals with upfronts, milestones, royalties, and term structures.
Primary-source-verified from SEC EDGAR, FTC filings, and direct research
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This analysis draws from the Ambrosia Ventures proprietary deal database (1,600+ verified biopharma transactions, 2019--2026). All deal terms are primary-source-verified from SEC EDGAR (10-K, 10-Q, 8-K filings), FTC pre-merger notifications, FDA Orange Book, and company press releases. No secondary-source or scraped data is included. Medians are calculated from deals with disclosed financial terms only.