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Colorectal Cancer — Deal Benchmarks & Valuation

Median Upfront
$316M
Range: $176M - $447M
Total Deal Value
$2.0B
Range: $1.3B - $2.7B
Royalty Rate
12.5% - 20.5%
Tiered up to 24.5%
Dev Milestones
$422M
Range: $282M - $565M

Market Analysis

Colorectal Cancer is one of the most actively transacted indications in oncology licensing. Phase 2 deals for colorectal cancer carry a median total deal value of $2.0B, with upfront payments ranging from $176M to $447M. The recommended deal structure allocates approximately 16% to upfront payments and 84% to milestones.

Milestone structures for colorectal cancer deals allocate $422M to development milestones, $676M to regulatory milestones, and $591M to commercial milestones. Royalty rates range from 12.5% to 20.5% at the base tier, with tiered escalation reaching 16.5%-24.5% on peak sales.

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Frequently Asked Questions

What are typical deal terms for colorectal cancer licensing?
Phase 2 colorectal cancer licensing deals average $316M in upfront payments with $2.0B total deal value. The 16/84 upfront/milestone split reflects the risk profile at this clinical stage.
What royalty rates are standard for colorectal cancer deals?
Base royalty rates for colorectal cancer transactions range from 12.5% to 20.5%, with tiered escalations reaching 16.5%-24.5% on peak sales. Rates are influenced by mechanism differentiation, competitive positioning, and territorial scope.
How are colorectal cancer deal milestones structured?
Colorectal Cancer deals allocate approximately 84% of total deal value to milestones. Development milestones ($422M) make up the largest share, followed by commercial milestones ($591M) and regulatory milestones ($676M).
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