Cholangiocarcinoma — Deal Benchmarks & Valuation
Market Analysis
Cholangiocarcinoma is one of the most actively transacted indications in oncology licensing. Phase 2 deals for cholangiocarcinoma carry a median total deal value of $1.6B, with upfront payments ranging from $140M to $355M. The recommended deal structure allocates approximately 16% to upfront payments and 84% to milestones.
Milestone structures for cholangiocarcinoma deals allocate $336M to development milestones, $537M to regulatory milestones, and $470M to commercial milestones. Royalty rates range from 11.7% to 19.1% at the base tier, with tiered escalation reaching 15.7%-23.1% on peak sales.
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Frequently Asked Questions
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